COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE

COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE

Compounds with two fused bicyclic heteroaryl moieties of formula I and their pharmaceutical compositions, and methods of using them as leukotriene A4 hydrolase (LTA4H) modulators and for the treatment of diseases, disorders and conditions mediated by LTA4H. Compuestos con dos entidades de heteroaril...

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Hauptverfasser: FOURIE, ANNE M, LEE-DUTRA, ALICE, LANDRY-BAYLE, ADRIENNE, GOMEZ, LAURENT, ECCLES, WENDY, TANIS, VIRGINIA M, GRICE, CHERYL A, CHROVIAN, CHRIST C, KEARNY, AARON M, SANTILLAN, ALEJANDRO, JR, BACANI, GENESIS M, WIENER, JOHN M
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compounds with two fused bicyclic heteroaryl moieties of formula I and their pharmaceutical compositions, and methods of using them as leukotriene A4 hydrolase (LTA4H) modulators and for the treatment of diseases, disorders and conditions mediated by LTA4H. Compuestos con dos entidades de heteroarilo bicíclico fusionado de la Fórmula I y sus composiciones farmacéuticas, y métodos para usarlos como moduladores de la leucotrieno A4 hidrolasa (LTA4H) y para el tratamiento de enfermedades, trastornos y afecciones mediadas por la LTA4H.