TRICYCLIC INDOLE DERIVATES AS PBR LIGANDS

An indole-based in vivo imaging agent is provided by the present invention that binds with high affinity to PBR, has good uptake into the brain following administration, and which has good selective binding to PBR. The invention also includes a precursor compound useful in the synthesis of the in vi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	WILLIAM JOHN TRIGG, BO SHAN, DENNIS O'SHEA, JOANNA MARIE PASSMORE, AMANDA EWAN, HARRY JOHN WADSWORTH
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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