TRI-CYCLIC PYRAZOLOPYRIDINE KINASE INHIBITORS

TRI-CYCLIC PYRAZOLOPYRIDINE KINASE INHIBITORS

The present invention relates to compounds useful as inhibitors of P13K, particularly of P13Kgamma. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of several diseases, such as cancer and autoimmune...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KEVIN COTTRELL, GABRIEL MARTINEZ-BOTELLA, DAVID MESSERSMITH, EMILIE PORTER HUCK, RONALD GREY, JON COME, AMAUD LE TIRAN, VALERIE MARONE, ALEX ARONOV
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to compounds useful as inhibitors of P13K, particularly of P13Kgamma. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of several diseases, such as cancer and autoimmune diseases. La presente invención se refiere a compuestos útiles como inhibidores de PI3K, particularmente de PI3lKgamma. La invención también proporciona composiciones farmacéuticamente aceptables que comprenden los compuestos y métodos para el uso de las composiciones en el tratamiento de diversas enfermedades, tales como cáncer y enfermedades autoinmunes.