MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR. (l); or pharmaceutically acceptable salts t...

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Bibliographische Detailangaben
Hauptverfasser:	HAYLEY BINCH, PETER D. J. GROOTENHUIS, LEV T.D. FANNING, XIAOQING YANG, FREDRICK VAN GOOR, DENNIS HURLEY, ALINA SILINA, URVI SHETH, MARTYN BOTFIELD, MEHDI MICHEL DJAMEL NUMA
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR. (l); or pharmaceutically acceptable salts thereof, wherein: ring A is selected from:. La presente invención se relaciona con moduladores del regulador de conductancia transmembrana de fibrosis quística ("CFTR"), las composiciones de los mismos, y los métodos con los mismos. La presente invención también se relaciona con los métodos para tratar enfermedades utilizando los moduladores del CFTR (1); o las sales farmacéuticamente aceptables de los mismos, en donde: el anillo A se selecciona de:.