PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES

Compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	XIAO QING LEWELL, CHARLOTTE JANE MITCHELL, STEPHEN ALLAN SMITH, DIANE MARY COE, KEITH BIGGADIKE, NAIMISHA TRIVEDI
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants. Se describen compuestos de fórmula (I): en la que R1 es alquil C1-6-amino, alcoxi C6-1 o cicloalquiloxi C3-7; m es un número entero que tiene un valor de 3 a 6; n es un número entero que tiene un valor de 0 a 4; y las sales de los mismos son inductores de interferón humano. Los compuestos que inducen interferón humano pueden ser útiles en el tratamiento de diversos trastornos, por ejemplo, el tratamiento de enfermedades alérgicas y otras afecciones inflamatorias, por ejemplo, rinitis alérgica y asma, el tratamiento de enfermedades infecciosas y cáncer, y también pueden ser útiles como adyuvantes de vacunas. (Ver fórmula (I)).