GAMMA SECRETASE MODULATORS

The present invention provides compounds that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for p...

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Bibliographische Detailangaben
Hauptverfasser:	QINGYIAN LIU, JEFFREY A. ADAMS, FRENEL DEMORIN, JIAWANG ZHU, JIAN J. CHEN, ESSA HU, CHESTER CHENGUANG YUAN, CHRISTOPHER M. TEGLEY, WENYUAN QIAN, ALBERT AMEGADZIE, ROXANNE KUNZ, NING CHEN, THOMAS NIXEY, TANYA PETERKIN, MQHELE NCUBE, STEPHEN HITCHCOCK, FRANK CHAVEZ JR
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds. La presente invención proporciona compuestos que son moduladores de gamma secretasa y por lo tanto son útiles para el tratamiento de enfermedades que pueden ser tratadas mediante la modulación de gamma secretasa tales como enfermedad de Alzheimer. Se proporcionan también composiciones farmacéuticas que contienen estos compuestos y procedimientos para preparar los compuestos.