5-CYANO-THIENOPYRIDINES FOR THE TREATMENT OF TUMORS

The invention relates to novel 5-cyano-thienopyridines of the formula (I) where R1, R2, and R3 have the meanings designated in Claim 1. Said 5-cyano-thienopyridines are inhibitors of TGF beta receptor kinase and may be used, among other things, for the treatment of tumors. Las nuevas 5-ciano-tienopi...

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Bibliographische Detailangaben
Hauptverfasser:	HARMUT GREINER, ULRICH GRAEDLER, PER HILLERTZ, DJORDJE MUSIL, CHRISTIANE AMENDT, GUENTER HOELZEMANN
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to novel 5-cyano-thienopyridines of the formula (I) where R1, R2, and R3 have the meanings designated in Claim 1. Said 5-cyano-thienopyridines are inhibitors of TGF beta receptor kinase and may be used, among other things, for the treatment of tumors. Las nuevas 5-ciano-tienopiridinas de la f?rmula I (ver f?rmula (I)) en donde R1, R2 y R3 tienen los significados indicados en la reivindicaci?n 1, son inhibidores de la quinasa del receptor TGF-beta, y se pueden emplear, por ejemplo, para el tratamiento de tumores.