TRIAZOLO [1, 5-A] QUINOLINES AS ADENOSINE A3 RECEPTOR LIGANDS

The present invention relates to the adenosine A3 receptor ligands of the general formula (I), within them favourably to the antagonists, to their salts, solvates, N-oxides and isomers, to the pharmaceutical compositions containing the compounds of the general formula (I), their salts, solvates, N-o...

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Hauptverfasser: KINGA BO?R, ZOLT?N KAPUI, EDIT SUS?N, S?NDOR B?TORI, TIBOR SZAB?, ZOLT?N SZL?VIK, KATALIN URB?N SZAB?, G?ZA T?M?RI, ENDRE MIKUS, JUDIT VARG?N? SZEREDI, MICHEL FINET
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention relates to the adenosine A3 receptor ligands of the general formula (I), within them favourably to the antagonists, to their salts, solvates, N-oxides and isomers, to the pharmaceutical compositions containing the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, to the use of the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, to the preparation of the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, as well as to the new intermediates of the general formula (II), (VI), (XI), (XII) and (XV), and to the preparation thereof. La presente invenci?n se refiere a los ligandos del receptor de adenosina A3 de f?rmula general (I), dentro de ellos favorablemente a los antagonistas, sus sales, solvatos, N-?xidos e is?meros, a las composiciones farmac?uticas que contienen los compuestos de f?rmula general (I), sus sales, solvatos, N-?xidos e is?meros, al uso de los compuestos de f?rmula general (I), sus sales, solvatos, N-?xidos e is?meros, a la preparaci?n de los compuestos de f?rmula general (I), sus sales, solvatos, N-?xidos e is?meros, as? como a los nuevos intermediarios de f?rmula general (II), (VI), (XI), (XII) y (XV) y a la preparaci?n de ellos.