RECOMBINANT ANTIBODIES AGAINST HEPATITIS C VIRUS AND METHODS OF OBTAINING AND USING SAME

Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection...

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Hauptverfasser: MARY S. PINKUS, ROBERT N. ZIEMANN, JOAN D. TYNER, BAILIN TU, ROBIN A. GUTIERREZ, DAVID J. HAWKSWORTH, MICHAEL K. WHITE, JAMES W. SCHEFFEL, JEFFREY M. WERNEKE
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creator MARY S. PINKUS
ROBERT N. ZIEMANN
JOAN D. TYNER
BAILIN TU
ROBIN A. GUTIERREZ
DAVID J. HAWKSWORTH
MICHAEL K. WHITE
JAMES W. SCHEFFEL
JEFFREY M. WERNEKE
description Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection of HCV, and/or as standardization reagents or positive control reagents in assays for the detection of HCV. The recombinant antibodies can also be used in the treatment or prevention of a HCV infection. Se proporcionan anticuerpos recombinantes, incluyendo anticuerpos quiméricos, específicos para proteínas antigénicas de hepatitis C (HCV). Los anticuerpos recombinantes específicamente se unen a regiones diagnósticamente relevantes y de esta manera son adecuados para usarse, por ejemplo, como reactivos de diagnóstico para la detección de HCV, y/o como reactivos de estandarización o reactivos de control positivos en ensayos para la detección de HCV. Los anticuerpos recombinantes también pueden ser utilizados en el tratamiento o prevención de una infección por HCV.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
SUGARS
TESTING
VINEGAR
WINE
title RECOMBINANT ANTIBODIES AGAINST HEPATITIS C VIRUS AND METHODS OF OBTAINING AND USING SAME
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