RECOMBINANT ANTIBODIES AGAINST HEPATITIS C VIRUS AND METHODS OF OBTAINING AND USING SAME

Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection...

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Bibliographische Detailangaben
Hauptverfasser:	MARY S. PINKUS, ROBERT N. ZIEMANN, JOAN D. TYNER, BAILIN TU, ROBIN A. GUTIERREZ, DAVID J. HAWKSWORTH, MICHAEL K. WHITE, JAMES W. SCHEFFEL, JEFFREY M. WERNEKE
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection of HCV, and/or as standardization reagents or positive control reagents in assays for the detection of HCV. The recombinant antibodies can also be used in the treatment or prevention of a HCV infection. Se proporcionan anticuerpos recombinantes, incluyendo anticuerpos quiméricos, específicos para proteínas antigénicas de hepatitis C (HCV). Los anticuerpos recombinantes específicamente se unen a regiones diagnósticamente relevantes y de esta manera son adecuados para usarse, por ejemplo, como reactivos de diagnóstico para la detección de HCV, y/o como reactivos de estandarización o reactivos de control positivos en ensayos para la detección de HCV. Los anticuerpos recombinantes también pueden ser utilizados en el tratamiento o prevención de una infección por HCV.