TARGETING OF ALPHA-1 OR ALPHA-3 SUBUNIT OF NA+, K+-ATPASE IN THE TREATMENT OF PROLIFERATIVE DISEASES

The present invention provides methods, reagents, pharmaceutical formulations and kits for the treatment of proliferative diseases, such as tumours and cancers. The invention teaches to target select subunits of the Na+,K+-ATPase, and especially the alpha-1 subunit and/or the alpha-3 subunit thereof...

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Bibliographische Detailangaben
Hauptverfasser:	FRANCIS DARRO, ERIC VAN QUAQUEBEKE, ROBERT KISS, TATJANA MIJATOVIC, LAURENT VAN DEN HOVE, NANCY DENEVE
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides methods, reagents, pharmaceutical formulations and kits for the treatment of proliferative diseases, such as tumours and cancers. The invention teaches to target select subunits of the Na+,K+-ATPase, and especially the alpha-1 subunit and/or the alpha-3 subunit thereof. La presente invención proporciona métodos, reactivos, formulaciones farmacéuticas y kits para el tratamiento de enfermedades proliferativas tales como tumores y cánceres. La invención describe dirigir subunidades seleccionadas de la Na+, K+.ATPasa, y especialmente la subunidad alfa-1 y/o la subunidad alfa-3 de la misma.