IMIDAZO[1,2-A]PYRIDINE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS

The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of pro...

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Bibliographische Detailangaben
Hauptverfasser:	ERIC T. SUN, KEN CHI LIK LEE
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC). Compuestos de hidroxamato que son inhibidores de la histona desacetilasa. Mas en particular, compuestos que contienen imidazo[1,2-a]piridina y metodos para su preparacion. Estos compuestos pueden ser de utilidad como medicamentos para el tratamiento de trastornos proliferativos, asi como otras enfermedades que incluyen, estan relacionadas o asociadas con enzimas que tienen actividad de las histona desacetilasas (HDAC).