AMINO-PYRIDINES AS INHIBITORS OF ????-SECRETASE
The present invention provides an amino-pyridine compound of formula (I). The present invention also provides methods for the use thereof to inhibit ??? -secretase (BACE) and treat ??? -amyloid deposits and neurofibrillary tangles. La presente invencion suministra un compuesto amino-piridina de form...
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| creator | MICHAEL SOTIRIOS MALAMAS WILLIAM RONALD SOLVIBILE, JR JEFFREY SCOTT CONDON ALBERT JEAN ROBICHAUD WILLIAM FLOYD FOBARE FRANK ELDRIDGE LOVERING |
| description | The present invention provides an amino-pyridine compound of formula (I). The present invention also provides methods for the use thereof to inhibit ??? -secretase (BACE) and treat ??? -amyloid deposits and neurofibrillary tangles.
La presente invencion suministra un compuesto amino-piridina de formula I (ver formula I) La presente invencion tambien suministra metodos para el uso de este para inhibir ???-secretasa (BACE) y tratar depositos ???-amiloides y ovillos neurofibrilares. |
| format | Patent |
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La presente invencion suministra un compuesto amino-piridina de formula I (ver formula I) La presente invencion tambien suministra metodos para el uso de este para inhibir ???-secretasa (BACE) y tratar depositos ???-amiloides y ovillos neurofibrilares.</description><language>eng ; spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2007</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070912&DB=EPODOC&CC=MX&NR=2007009313A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070912&DB=EPODOC&CC=MX&NR=2007009313A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MICHAEL SOTIRIOS MALAMAS</creatorcontrib><creatorcontrib>WILLIAM RONALD SOLVIBILE, JR</creatorcontrib><creatorcontrib>JEFFREY SCOTT CONDON</creatorcontrib><creatorcontrib>ALBERT JEAN ROBICHAUD</creatorcontrib><creatorcontrib>WILLIAM FLOYD FOBARE</creatorcontrib><creatorcontrib>FRANK ELDRIDGE LOVERING</creatorcontrib><title>AMINO-PYRIDINES AS INHIBITORS OF ????-SECRETASE</title><description>The present invention provides an amino-pyridine compound of formula (I). The present invention also provides methods for the use thereof to inhibit ??? -secretase (BACE) and treat ??? -amyloid deposits and neurofibrillary tangles.
La presente invencion suministra un compuesto amino-piridina de formula I (ver formula I) La presente invencion tambien suministra metodos para el uso de este para inhibir ???-secretasa (BACE) y tratar depositos ???-amiloides y ovillos neurofibrilares.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2007</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB39PX089cNiAzydPH0cw1WcAxW8PTz8HTyDPEPClbwd1OwBwLdYFfnINcQx2BXHgbWtMSc4lReKM3NoOTmGuLsoZtakB-fWlyQmJyal1oS7xthZGBgbmBgaWxo7GhMlCIARr0mVg</recordid><startdate>20070912</startdate><enddate>20070912</enddate><creator>MICHAEL SOTIRIOS MALAMAS</creator><creator>WILLIAM RONALD SOLVIBILE, JR</creator><creator>JEFFREY SCOTT CONDON</creator><creator>ALBERT JEAN ROBICHAUD</creator><creator>WILLIAM FLOYD FOBARE</creator><creator>FRANK ELDRIDGE LOVERING</creator><scope>EVB</scope></search><sort><creationdate>20070912</creationdate><title>AMINO-PYRIDINES AS INHIBITORS OF ????-SECRETASE</title><author>MICHAEL SOTIRIOS MALAMAS ; WILLIAM RONALD SOLVIBILE, JR ; JEFFREY SCOTT CONDON ; ALBERT JEAN ROBICHAUD ; WILLIAM FLOYD FOBARE ; FRANK ELDRIDGE LOVERING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX2007009313A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2007</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MICHAEL SOTIRIOS MALAMAS</creatorcontrib><creatorcontrib>WILLIAM RONALD SOLVIBILE, JR</creatorcontrib><creatorcontrib>JEFFREY SCOTT CONDON</creatorcontrib><creatorcontrib>ALBERT JEAN ROBICHAUD</creatorcontrib><creatorcontrib>WILLIAM FLOYD FOBARE</creatorcontrib><creatorcontrib>FRANK ELDRIDGE LOVERING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MICHAEL SOTIRIOS MALAMAS</au><au>WILLIAM RONALD SOLVIBILE, JR</au><au>JEFFREY SCOTT CONDON</au><au>ALBERT JEAN ROBICHAUD</au><au>WILLIAM FLOYD FOBARE</au><au>FRANK ELDRIDGE LOVERING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AMINO-PYRIDINES AS INHIBITORS OF ????-SECRETASE</title><date>2007-09-12</date><risdate>2007</risdate><abstract>The present invention provides an amino-pyridine compound of formula (I). The present invention also provides methods for the use thereof to inhibit ??? -secretase (BACE) and treat ??? -amyloid deposits and neurofibrillary tangles.
La presente invencion suministra un compuesto amino-piridina de formula I (ver formula I) La presente invencion tambien suministra metodos para el uso de este para inhibir ???-secretasa (BACE) y tratar depositos ???-amiloides y ovillos neurofibrilares.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AMINO-PYRIDINES AS INHIBITORS OF ????-SECRETASE |
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