AMINO-PYRIDINES AS INHIBITORS OF ????-SECRETASE

The present invention provides an amino-pyridine compound of formula (I). The present invention also provides methods for the use thereof to inhibit ??? -secretase (BACE) and treat ??? -amyloid deposits and neurofibrillary tangles. La presente invencion suministra un compuesto amino-piridina de form...

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Bibliographische Detailangaben
Hauptverfasser:	MICHAEL SOTIRIOS MALAMAS, WILLIAM RONALD SOLVIBILE, JR, JEFFREY SCOTT CONDON, ALBERT JEAN ROBICHAUD, WILLIAM FLOYD FOBARE, FRANK ELDRIDGE LOVERING
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides an amino-pyridine compound of formula (I). The present invention also provides methods for the use thereof to inhibit ??? -secretase (BACE) and treat ??? -amyloid deposits and neurofibrillary tangles. La presente invencion suministra un compuesto amino-piridina de formula I (ver formula I) La presente invencion tambien suministra metodos para el uso de este para inhibir ???-secretasa (BACE) y tratar depositos ???-amiloides y ovillos neurofibrilares.