SUBSTITUTED 5-OXO PYRAZOLES AND [1,2,4]TRIAZOLES AS ANTIVIRAL AGENTS

The present invention provides compounds of formula (I) wherein X and R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorders using these compounds and compositions are also provi...

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Bibliographische Detailangaben
Hauptverfasser:	COOPER, ALAN B, GIRIJAVALLABHAN, VIYYOOR MOOPIL, ROSNER, KRISTEN E, WANG, TONG, SHIPPS, GERALD W., JR, CURRAN, PATRICK J
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds of formula (I) wherein X and R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorders using these compounds and compositions are also provided. La presente invencion provee compuestos de formula I (ver formula I) en donde X, R1-R7 son como se definen aqui; las composiciones que contiene estos compuestos, y metodos para la inhibicion de polimerasa de ARN dependiente de ARN de HCV y el tratamiento de hepatitis C y trastornos relacionados usando estos compuestos y composiciones tambien se proveen.