PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE BENZOATO DE 6-AMIDINO-2-NAFTILO

PCT No. PCT/JP85/00392 Sec. 371 Date Feb. 24, 1986 Sec. 102(e) Date Feb. 24, 1986 PCT Filed Jul. 12, 1985 PCT Pub. No. WO86/00893 PCT Pub. Date Feb. 13, 1986.Amidine compounds of formula (I) (I) and the pharmaceutically acceptable acid addition salts thereof are novel and are of use as anti-trypsin,...

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Hauptverfasser:	TOSHIYUKI OKUTOME, TOYOO NAKAYAMA, SETSURO FUJII
Format:	Patent
Sprache:	spa
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	PCT No. PCT/JP85/00392 Sec. 371 Date Feb. 24, 1986 Sec. 102(e) Date Feb. 24, 1986 PCT Filed Jul. 12, 1985 PCT Pub. No. WO86/00893 PCT Pub. Date Feb. 13, 1986.Amidine compounds of formula (I) (I) and the pharmaceutically acceptable acid addition salts thereof are novel and are of use as anti-trypsin, anti-plasmin, anti-kallikrein, anti-thrombin and anti-complement agents which may be administered orally. These amidine compounds can be produced by the reaction between a carboxylic acid compound of formula (II) (II) or a reactive intermediate thereof and 6-amidino-2-naphthol of formula (III) (III) or preferably an acid addition salt thereof.