TRIAZOLO [1, 5-A] QUINOLINES AS ADENOSINE A3 RECEPTOR LIGANDS

Predmetni pronalazak se odnosi na ligande adenozin A3 receptora opšte formule (I), među njima, poželjno je na antagoniste, njihove soli, solvate, N-okside i izomere, na farmaceutske preparate koji sadrže jedinjenja prema opštoj formuli (I), njihove soli, solvate, N-okside i izomere, na upotrebu jedinjenja prema opštoj formuli (I), njihovih soli, solvata, N­ oksida i izomera, na dobijanje jedinjenja prema opštoj formuli (I), njihovih soli, solvata, N­ oksida i izomera kao i na nove intermedijere opšte formule (II), (VI), (XI), (XII) i (XV) i na njihovo dobijanje. The present invention relates to the adenosine A3 receptor ligands of the general formula (I), within them favourably to the antagonists, to their salts, solvates, N-oxides and isomers, to the pharmaceutical compositions containing the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, to the use of the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, to the preparation of the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, as well as to the new intermediates of the general formula (II), (VI), (XI), (XII) and (XV), and to the preparation thereof.