CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO) ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE) METHYL]-2, 4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF
Ovaj pronalazak opisuje kristale,i njihove preparate, gde kristali uključuju N-[2- (dietilamino)etil]-5-[(5-fluoro-1,2-dihidro-2-okso-J H-indol-3-iliden)metil]-2,4-dimetil-1 H-pirol-3-karboksamid so jabučne kiseline. Takođe su opisani postupci za pripremu takvih kristala. The present invention...
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creator | HAWLEY, Michael MALONEY, Mark, T PRESCOTT, Stephen, P FLECK, Thomas, J |
description | Ovaj pronalazak opisuje kristale,i njihove preparate, gde kristali uključuju N-[2- (dietilamino)etil]-5-[(5-fluoro-1,2-dihidro-2-okso-J H-indol-3-iliden)metil]-2,4-dimetil-1 H-pirol-3-karboksamid so jabučne kiseline. Takođe su opisani postupci za pripremu takvih kristala.
The present invention provides a crystal comprising the L-malic acid salt of N-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide, wherein the crystal has characteristic diffraction peaks at 13.2 and 24.2 degrees two-theta in a powder X-ray diffraction pattern, for use as a medicament. |
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The present invention provides a crystal comprising the L-malic acid salt of N-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide, wherein the crystal has characteristic diffraction peaks at 13.2 and 24.2 degrees two-theta in a powder X-ray diffraction pattern, for use as a medicament.</description><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111010&DB=EPODOC&CC=ME&NR=00414B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25568,76551</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111010&DB=EPODOC&CC=ME&NR=00414B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HAWLEY, Michael</creatorcontrib><creatorcontrib>MALONEY, Mark, T</creatorcontrib><creatorcontrib>PRESCOTT, Stephen, P</creatorcontrib><creatorcontrib>FLECK, Thomas, J</creatorcontrib><title>CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO) ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE) METHYL]-2, 4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF</title><description>Ovaj pronalazak opisuje kristale,i njihove preparate, gde kristali uključuju N-[2- (dietilamino)etil]-5-[(5-fluoro-1,2-dihidro-2-okso-J H-indol-3-iliden)metil]-2,4-dimetil-1 H-pirol-3-karboksamid so jabučne kiseline. Takođe su opisani postupci za pripremu takvih kristala.
The present invention provides a crystal comprising the L-malic acid salt of N-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide, wherein the crystal has characteristic diffraction peaks at 13.2 and 24.2 degrees two-theta in a powder X-ray diffraction pattern, for use as a medicament.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjM9qAjEQxvfSQ9E-QmGOCg7o7voAMZk0A0lmSSK4SBEp6alYwb5o36i2eu_p-_fje2y-dRpzUT4DR-23huMLKAjKswal2UBWvoBYiLhvcWaYihu9ChxlDn_-Fde4n63R-q0kwRZlJ9g55GjEE3Y4ejYUaQ7hzrcL6NHwLeLK4TCmdGO1ShvZXe8NLWBIoilnymAlAZd8bWhQSRWWCCoa0BIGyfybMxRHicROm4f348elPt110jxbKtphPX8e6uV8fKun-nUItFz2q37T_bf_AFOMT3Q</recordid><startdate>20111010</startdate><enddate>20111010</enddate><creator>HAWLEY, Michael</creator><creator>MALONEY, Mark, T</creator><creator>PRESCOTT, Stephen, P</creator><creator>FLECK, Thomas, J</creator><scope>EVB</scope></search><sort><creationdate>20111010</creationdate><title>CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO) ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE) METHYL]-2, 4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF</title><author>HAWLEY, Michael ; MALONEY, Mark, T ; PRESCOTT, Stephen, P ; FLECK, Thomas, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ME00414B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2011</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HAWLEY, Michael</creatorcontrib><creatorcontrib>MALONEY, Mark, T</creatorcontrib><creatorcontrib>PRESCOTT, Stephen, P</creatorcontrib><creatorcontrib>FLECK, Thomas, J</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HAWLEY, Michael</au><au>MALONEY, Mark, T</au><au>PRESCOTT, Stephen, P</au><au>FLECK, Thomas, J</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO) ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE) METHYL]-2, 4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF</title><date>2011-10-10</date><risdate>2011</risdate><abstract>Ovaj pronalazak opisuje kristale,i njihove preparate, gde kristali uključuju N-[2- (dietilamino)etil]-5-[(5-fluoro-1,2-dihidro-2-okso-J H-indol-3-iliden)metil]-2,4-dimetil-1 H-pirol-3-karboksamid so jabučne kiseline. Takođe su opisani postupci za pripremu takvih kristala.
The present invention provides a crystal comprising the L-malic acid salt of N-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide, wherein the crystal has characteristic diffraction peaks at 13.2 and 24.2 degrees two-theta in a powder X-ray diffraction pattern, for use as a medicament.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO) ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE) METHYL]-2, 4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF |
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