CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO) ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE) METHYL]-2, 4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF

CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO) ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE) METHYL]-2, 4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF

Ovaj pronalazak opisuje kristale,i njihove preparate, gde kristali  uključuju  N-[2- (dietilamino)etil]-5-[(5-fluoro-1,2-dihidro-2-okso-J H-indol-3-iliden)metil]-2,4-dimetil-1 H-pirol-3-karboksamid so jabučne  kiseline. Takođe su opisani  postupci  za pripremu takvih kristala. The present invention...

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Bibliographische Detailangaben
Hauptverfasser: HAWLEY, Michael, MALONEY, Mark, T, PRESCOTT, Stephen, P, FLECK, Thomas, J
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Ovaj pronalazak opisuje kristale,i njihove preparate, gde kristali  uključuju  N-[2- (dietilamino)etil]-5-[(5-fluoro-1,2-dihidro-2-okso-J H-indol-3-iliden)metil]-2,4-dimetil-1 H-pirol-3-karboksamid so jabučne  kiseline. Takođe su opisani  postupci  za pripremu takvih kristala. The present invention provides a crystal comprising the L-malic acid salt of N-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide, wherein the crystal has characteristic diffraction peaks at 13.2 and 24.2 degrees two-theta in a powder X-ray diffraction pattern, for use as a medicament.