Pyrrolo[2,3-d]pyrimidine derivatives as inhibitors of Janus-related Kinases (JAK)

The invention relates to pharmaceutically active pyrollo[2,3-d]pyrimidine derivatives.According to the invention, claimed are pyrrolo[2,3-d]pyrimidine derivatives of Formula IA:Also, claimed is their use as Janus Kinase (JAK) inhibitors and pharmaceutical compositions containing them. Invenţia se re...

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Bibliographische Detailangaben
Hauptverfasser:	TENBRINK Ruth E, UNWALLA Rayomand Jal, BROWN Matthew Frank, KAILA Neelu, FENWICK Ashley Edward, MITTON-FRY Mark J, PARIKH Mihir D, FLANAGAN Mark Edward, JOHNSON Timothy Allan, STROHBACH Joseph Walter, GONZALES Andrea, TRZUPEK John David, VAZQUEZ Michael L
Format:	Patent
Sprache:	eng ; rum ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to pharmaceutically active pyrollo[2,3-d]pyrimidine derivatives.According to the invention, claimed are pyrrolo[2,3-d]pyrimidine derivatives of Formula IA:Also, claimed is their use as Janus Kinase (JAK) inhibitors and pharmaceutical compositions containing them. Invenţia se referă la derivaţi ai pirolo[2,3-d]pirimidinei farmaceutic activi. Conform invenţiei, se revendică derivaţi ai pirolo[2,3-d]pirimidinei cu formula IA: De asemenea, se revendică utilizarea lor în calitate de inhibitori de Kinaze Janus (JAK) şi compoziţii farmaceutice care îi conţin. Изобретение относится к фармацевтически активным производным пиролло[2,3-d]пиримидина.Согласно изобретению, заявляются производные пиролло[2,3-d]пиримидина с формулой IA: Также, заявляется их применение в качестве ингибиторов Янус Киназ (JAK) и содержащие их фармацевтические композиции.