Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties

The invention relates to organic compounds from the class of thiosemicarbazones possessing antibacterial activity. The compounds can be used in medicine, veterinary medicine and agriculture.Summary of the invention consists in the synthesis of new derivatives of 4-formyl-3-hydroxy-2-naphthoic acid o...

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Hauptverfasser: COJOCARI DANIELA, GONCIAR VEACESLAV, TURT CONSTANTIN, GONCHYAR VYACHESLAV, BOUROSH PAULINA, BOURO POLINA, LAZARESCU ANA, ZARICIUC ELENA, TURTA CONSTANTIN
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creator COJOCARI DANIELA
GONCIAR VEACESLAV
TURT CONSTANTIN
GONCHYAR VYACHESLAV
BOUROSH PAULINA
BOURO POLINA
LAZARESCU ANA
ZARICIUC ELENA
TURTA CONSTANTIN
description The invention relates to organic compounds from the class of thiosemicarbazones possessing antibacterial activity. The compounds can be used in medicine, veterinary medicine and agriculture.Summary of the invention consists in the synthesis of new derivatives of 4-formyl-3-hydroxy-2-naphthoic acid of the formula:where R = H (1) and C6H5 (2). The compounds exhibit bacteriostatic and bactericidal properties against pathogens S. aureus and E. coli. Invenţia se referă la compuşi organici din clasa tiosemicarbazonelor care posedă activitate antibacteriană. Compuşii pot fi utilizaţi în medicină, medicina veterinară şi agricultură.Esenţa invenţiei constă în sinteza derivaţilor noi ai acidului 4-formil-3-hidroxi-2-naftoic cu formula:unde R = H (1) şi C6H5 (2). Compuşii manifestă proprietăţi bacteriostatice şi bactericide faţă de microorganismele patogene S. aureus şi E.coli.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties
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