COMPOSÉS 3-CARBONYLAMINO-5-CYCLOPENTYL-1H-PYRAZOLE AYANT UNE ACTIVITÉ INHIBITRICE DE CDK2

This invention relates to compounds of Formula (I)and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and...

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Bibliographische Detailangaben
Hauptverfasser:	FREEMAN-COOK, Kevin Daniel, SUTTON, Scott Channing, NAGATA, Asako, BEHENNA, Douglas Carl, NINKOVIC, Sacha, HOFFMAN, Robert Louis
Format:	Patent
Sprache:	fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to compounds of Formula (I)and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.