COMPOSÉS, COMPOSITIONS PHARMACEUTIQUES, PROCÉDÉS DE PRÉPARATION DE COMPOSÉS ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE KINASE ATR

COMPOSÉS, COMPOSITIONS PHARMACEUTIQUES, PROCÉDÉS DE PRÉPARATION DE COMPOSÉS ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE KINASE ATR

Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions contai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DORICH, Stéphane, LANOIX, Stéphanie, JONES, Paul, BLACK, Cameron, TRUONG, Vouy Linh, TRUCHON, Jean-François, ABDOLI, Abbas, CRANE, Sheldon N, FADER, Lee, PICARD, Audrey, LACBAY, Cyrus M, ST-ONGE, Miguel
Format: Patent
Sprache:fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.