INHIBITEURS DE TGF?1 SÉLECTIFS SELON L'ISOFORME À AFFINITÉ ÉLEVÉE
Disclosed herein are monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGFβ1 with high potency. Related compositions, methods and therapeutic use are also disclosed.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | CHAPRON, Christopher WAWERSIK, Stefan STEIN, Caitlin BUCKLER, Alan COOPER, Anthony JACKSON, Justin, W LIN, Susan SCHURPF, Thomas DAGBAY, Kevin, B CAPILI, Allan DATTA, Abhishek SALOTTO, Matthew AVERY, Andrew MARTIN, Constance LITTLEFIELD, Christopher CARVEN, Gregory, J |
| description | Disclosed herein are monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGFβ1 with high potency. Related compositions, methods and therapeutic use are also disclosed. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_MA53125A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>MA53125A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_MA53125A3</originalsourceid><addsrcrecordid>eNrjZHDz9PPwdPIMcQ0NClZwcVUIcXezN1QIPtzp4-oc4ukWrBDs6uPvp-Cj7hns7-Yf5OuqcLhBwdENqM0z5HCnAkhd2OFOVx4G1rTEnOJUXijNzSDr5hri7KGbWpAfn1pckJicmpdaEu_raGpsaGTqaExIHgCeNi30</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>INHIBITEURS DE TGF?1 SÉLECTIFS SELON L'ISOFORME À AFFINITÉ ÉLEVÉE</title><source>esp@cenet</source><creator>CHAPRON, Christopher ; WAWERSIK, Stefan ; STEIN, Caitlin ; BUCKLER, Alan ; COOPER, Anthony ; JACKSON, Justin, W ; LIN, Susan ; SCHURPF, Thomas ; DAGBAY, Kevin, B ; CAPILI, Allan ; DATTA, Abhishek ; SALOTTO, Matthew ; AVERY, Andrew ; MARTIN, Constance ; LITTLEFIELD, Christopher ; CARVEN, Gregory, J</creator><creatorcontrib>CHAPRON, Christopher ; WAWERSIK, Stefan ; STEIN, Caitlin ; BUCKLER, Alan ; COOPER, Anthony ; JACKSON, Justin, W ; LIN, Susan ; SCHURPF, Thomas ; DAGBAY, Kevin, B ; CAPILI, Allan ; DATTA, Abhishek ; SALOTTO, Matthew ; AVERY, Andrew ; MARTIN, Constance ; LITTLEFIELD, Christopher ; CARVEN, Gregory, J</creatorcontrib><description>Disclosed herein are monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGFβ1 with high potency. Related compositions, methods and therapeutic use are also disclosed.</description><language>fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210519&DB=EPODOC&CC=MA&NR=53125A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210519&DB=EPODOC&CC=MA&NR=53125A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHAPRON, Christopher</creatorcontrib><creatorcontrib>WAWERSIK, Stefan</creatorcontrib><creatorcontrib>STEIN, Caitlin</creatorcontrib><creatorcontrib>BUCKLER, Alan</creatorcontrib><creatorcontrib>COOPER, Anthony</creatorcontrib><creatorcontrib>JACKSON, Justin, W</creatorcontrib><creatorcontrib>LIN, Susan</creatorcontrib><creatorcontrib>SCHURPF, Thomas</creatorcontrib><creatorcontrib>DAGBAY, Kevin, B</creatorcontrib><creatorcontrib>CAPILI, Allan</creatorcontrib><creatorcontrib>DATTA, Abhishek</creatorcontrib><creatorcontrib>SALOTTO, Matthew</creatorcontrib><creatorcontrib>AVERY, Andrew</creatorcontrib><creatorcontrib>MARTIN, Constance</creatorcontrib><creatorcontrib>LITTLEFIELD, Christopher</creatorcontrib><creatorcontrib>CARVEN, Gregory, J</creatorcontrib><title>INHIBITEURS DE TGF?1 SÉLECTIFS SELON L'ISOFORME À AFFINITÉ ÉLEVÉE</title><description>Disclosed herein are monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGFβ1 with high potency. Related compositions, methods and therapeutic use are also disclosed.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHDz9PPwdPIMcQ0NClZwcVUIcXezN1QIPtzp4-oc4ukWrBDs6uPvp-Cj7hns7-Yf5OuqcLhBwdENqM0z5HCnAkhd2OFOVx4G1rTEnOJUXijNzSDr5hri7KGbWpAfn1pckJicmpdaEu_raGpsaGTqaExIHgCeNi30</recordid><startdate>20210519</startdate><enddate>20210519</enddate><creator>CHAPRON, Christopher</creator><creator>WAWERSIK, Stefan</creator><creator>STEIN, Caitlin</creator><creator>BUCKLER, Alan</creator><creator>COOPER, Anthony</creator><creator>JACKSON, Justin, W</creator><creator>LIN, Susan</creator><creator>SCHURPF, Thomas</creator><creator>DAGBAY, Kevin, B</creator><creator>CAPILI, Allan</creator><creator>DATTA, Abhishek</creator><creator>SALOTTO, Matthew</creator><creator>AVERY, Andrew</creator><creator>MARTIN, Constance</creator><creator>LITTLEFIELD, Christopher</creator><creator>CARVEN, Gregory, J</creator><scope>EVB</scope></search><sort><creationdate>20210519</creationdate><title>INHIBITEURS DE TGF?1 SÉLECTIFS SELON L'ISOFORME À AFFINITÉ ÉLEVÉE</title><author>CHAPRON, Christopher ; WAWERSIK, Stefan ; STEIN, Caitlin ; BUCKLER, Alan ; COOPER, Anthony ; JACKSON, Justin, W ; LIN, Susan ; SCHURPF, Thomas ; DAGBAY, Kevin, B ; CAPILI, Allan ; DATTA, Abhishek ; SALOTTO, Matthew ; AVERY, Andrew ; MARTIN, Constance ; LITTLEFIELD, Christopher ; CARVEN, Gregory, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MA53125A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fre</language><creationdate>2021</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHAPRON, Christopher</creatorcontrib><creatorcontrib>WAWERSIK, Stefan</creatorcontrib><creatorcontrib>STEIN, Caitlin</creatorcontrib><creatorcontrib>BUCKLER, Alan</creatorcontrib><creatorcontrib>COOPER, Anthony</creatorcontrib><creatorcontrib>JACKSON, Justin, W</creatorcontrib><creatorcontrib>LIN, Susan</creatorcontrib><creatorcontrib>SCHURPF, Thomas</creatorcontrib><creatorcontrib>DAGBAY, Kevin, B</creatorcontrib><creatorcontrib>CAPILI, Allan</creatorcontrib><creatorcontrib>DATTA, Abhishek</creatorcontrib><creatorcontrib>SALOTTO, Matthew</creatorcontrib><creatorcontrib>AVERY, Andrew</creatorcontrib><creatorcontrib>MARTIN, Constance</creatorcontrib><creatorcontrib>LITTLEFIELD, Christopher</creatorcontrib><creatorcontrib>CARVEN, Gregory, J</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHAPRON, Christopher</au><au>WAWERSIK, Stefan</au><au>STEIN, Caitlin</au><au>BUCKLER, Alan</au><au>COOPER, Anthony</au><au>JACKSON, Justin, W</au><au>LIN, Susan</au><au>SCHURPF, Thomas</au><au>DAGBAY, Kevin, B</au><au>CAPILI, Allan</au><au>DATTA, Abhishek</au><au>SALOTTO, Matthew</au><au>AVERY, Andrew</au><au>MARTIN, Constance</au><au>LITTLEFIELD, Christopher</au><au>CARVEN, Gregory, J</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INHIBITEURS DE TGF?1 SÉLECTIFS SELON L'ISOFORME À AFFINITÉ ÉLEVÉE</title><date>2021-05-19</date><risdate>2021</risdate><abstract>Disclosed herein are monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGFβ1 with high potency. Related compositions, methods and therapeutic use are also disclosed.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | fre |
| recordid | cdi_epo_espacenet_MA53125A |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | INHIBITEURS DE TGF?1 SÉLECTIFS SELON L'ISOFORME À AFFINITÉ ÉLEVÉE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T21%3A37%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CHAPRON,%20Christopher&rft.date=2021-05-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EMA53125A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |