DÉRIVÉS DE GIP ET LEURS UTILISATIONS

The present invention relates to novel peptides that are derivatives of glucose-dependent insulinotropic polypeptide (GIP) analogues having improved physical stability in solution and a protracted profile of action. More particular the invention relates to such peptides that are agonists at the GIP...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	FINAN, Brian, LAU, Jesper F, COX, Nicholas Raymond, HOGENDORF, Wouter Frederik Johan, KNERR, Patrick J, REEDTZ-RUNGE, Steffen, THØGERSEN, Henning, DIMARCHI, Richard, LIU, Fa
Format:	Patent
Sprache:	fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to novel peptides that are derivatives of glucose-dependent insulinotropic polypeptide (GIP) analogues having improved physical stability in solution and a protracted profile of action. More particular the invention relates to such peptides that are agonists at the GIP receptor and to their use in weight management or for treatment of diseases such as obesity, diabetes or non-alcoholic steatohepatitis (NASH).