NOUVEAUX COMPOSÉS ET COMPOSITIONS PHARMACEUTIQUES DE CEUX-CI DESTINÉS AU TRAITEMENT DE LA FIBROSE

The present invention discloses compounds according to Formula I:Wherein R1, R2, L, A1, A2, A3, Cy and the subscript n are as defined herein.The present invention relates to antagonists compounds of sphingosine 1-phosphate (S1P) receptor, methods for their production, pharmaceutical compositions com...

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Bibliographische Detailangaben
Hauptverfasser:	EL BKASSINY, Sandy, TRICARICO, Giovanni, Alessandro, ALLART, Brigitte, JAUNET, Alexis, Patrick, Claude, DUTHION, Béranger, MAMMOLITI, Oscar, BREBION, Franck Laurent, JANSEN, Koen, Karel, PALISSE, Adeline, Marie, Elise, MENET, Christel, Jeanne, Marie
Format:	Patent
Sprache:	fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention discloses compounds according to Formula I:Wherein R1, R2, L, A1, A2, A3, Cy and the subscript n are as defined herein.The present invention relates to antagonists compounds of sphingosine 1-phosphate (S1P) receptor, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, inflammatory diseases, respiratory diseases, autoimmune diseases, metabolic diseases, cardiovascular diseases, and/or proliferative diseases by administering the compound of the invention.