INHIBITEURS DE KRAS G12C ET LEURS PROCÉDÉS D'UTILISATION

Provided herein are KRAS G12C inhibitors, such ascomposition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

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Bibliographische Detailangaben
Hauptverfasser:	CHU-MOYER, Margaret, SIEGMUND, Aaron C, SHIN, Youngsook, ALLEN, Jennifer Rebecca, AMEGADZIE, Albert, WANG, Hui-Ling, LANMAN, Brian Alan, NGUYEN, Thomas T, MINATTI, Ana Elena, BOOKER, Shon, PICKRELL, Alexander J, YANG, Kevin C, WURZ, Ryan Paul, WALTON, Mary, REED, Anthony B, LOW, Jonathan D, TAMAYO, Nuria A, CEE, Victor J, LOPEZ, Patricia, ALLEN, John Gordon, XUE, Qiufen, MA, Vu Van, CHEN, Jian, GOODMAN, Clifford, LIU, Longbin, CHEN, Ning, NISHIMURA, Nobuko
Format:	Patent
Sprache:	fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are KRAS G12C inhibitors, such ascomposition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.