COMPOSÉS DE TRIAZOLE SUBSTITUÉS PAR ALKYLE EN TANT QU'AGONISTES DU RÉCEPTEUR APJ

COMPOSÉS DE TRIAZOLE SUBSTITUÉS PAR ALKYLE EN TANT QU'AGONISTES DU RÉCEPTEUR APJ

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following stru...

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Bibliographische Detailangaben
Hauptverfasser: RAMSDEN, Philip Dean, DRANSFIELD, Paul John, YEH, Wen-Chen, HOUZE, Jonathan, MA, Zhihua, DEBENEDETTO, Mikkel V, LAI, Su-Jen, HARVEY, James S, PATTAROPONG, Vatee, CHEN, Yinhong, KHAKOO, Aarif Yusuf, SHARMA, Ankit, SWAMINATH, Gayathri, NISHIMURA, Nobuko
Format: Patent
Sprache:fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: (I), (II) where the definitions of the variables are provided herein.