ANTICORPS SPÉCIFIQUES DE LA PROTÉINE TAU HYPERPHOSPHORYLÉE ET LEURS PROCÉDÉS D'UTILISATION

The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer'...

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Bibliographische Detailangaben
Hauptverfasser:	ABDUR-RASHEED ASUNI, Ayodeji, PEDERSEN, Jan, Torleif, DÄCHSEL, Justus, Claus, Alfred, ROSENQVIST, Nina, PEDERSEN, Lars, Østergaard
Format:	Patent
Sprache:	fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.