MÉTHODES POUR LA PRÉPARATION DE RIBOSIDES

Provided are methods of preparing compounds and pharmaceutical compositions for treating Filoviridae virus infections. The compounds, compositions, and methods provided are particularly useful for the treatment of Marburg virus, Ebola virus and Cueva virus infections.A method preparing a compound of...

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Hauptverfasser: HEUMANN, Lars, V, STEVENS, Andrew, C, GAO, Detian, BRAK, Katrien, TADEUS, Clarissa, YU, Chia-Yun, BADALOV, Pavel, Robertovich, CAMPAGNA, Silvio, CHTELININE, Andrei, ROSS, Bruce, HOANG, Brittanie, RUEDEN, Erick, NEVILLE, Sean, Timothy, SCOTT, Robert William, WHITCOMB, Mark Charles, SIEGEL, Dustin, VIEIRA, Tiago, AXT, Steven, Donald, WOLFE, Lydia, DOERFFLER, Edward, LEW, Willard, MILBURN, Robert, Ronald, WANG, Xianghong, FRICK, Morin, Mae, WALTMAN, Andrew W
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Sprache:fre
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Zusammenfassung:Provided are methods of preparing compounds and pharmaceutical compositions for treating Filoviridae virus infections. The compounds, compositions, and methods provided are particularly useful for the treatment of Marburg virus, Ebola virus and Cueva virus infections.A method preparing a compound of Formula (XI-a2) is disclosed: