PROCEDE POUR LA PREPARATION DE COMPOSITIONS VACCINANTES

Novel vaccine compositions comprising small particles of 3-O-deacylated monophosphoryl lipid A are provided. In particular the particle size are small enough to be filtered through a 220 nm membrane, and in general are below 120 nm. Such vaccine compositions have superior immunological properties.

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Bibliographische Detailangaben
Hauptverfasser: MONCEF SLAOUI, PIERRE HAUSER, N.M. JOSEPHE C.G-J, PIERRE VOET, P. DESMONS
Format: Patent
Sprache:fre
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Zusammenfassung:Novel vaccine compositions comprising small particles of 3-O-deacylated monophosphoryl lipid A are provided. In particular the particle size are small enough to be filtered through a 220 nm membrane, and in general are below 120 nm. Such vaccine compositions have superior immunological properties.