Glikopeptidi kuriem piemit pretaudzeju aktivitate un to iegusanas panemiens

Glycopeptides according to the present invention have the formula: (I) wherein n=1 or 2; R is a residue of an aminoacid or linear peptides built of 2 to 5 amino acid residues. These compounds are prepared by the method involving condensation of unblocked muramyl-containing N-acetylamino-sugars of th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	IRINA SOROKINA, VADIM IVANOV, TATJANA ANDRONOVA, JURIJ OVCHINNIKOV, LARISA ROSTOVCEVA, VERONIKA MALKOVA
Format:	Patent
Sprache:	lav
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Glycopeptides according to the present invention have the formula: (I) wherein n=1 or 2; R is a residue of an aminoacid or linear peptides built of 2 to 5 amino acid residues. These compounds are prepared by the method involving condensation of unblocked muramyl-containing N-acetylamino-sugars of the formula: (II) wherein n=1 or 2, with blocked aminoacids or peptides. The method of this invention makes it possible to produce synthetic glycopeptides manifesting a biological activity. These compounds possess an antitumor and adjuvant activity.