METHOD OF PROGNOSIS OF RISK OF SUDDEN DEATH IN PATIENTS WITH HIV AND TUBERCULOSIS CO-INFECTION (HIV/TB) INCLUDING CASE OF IRIS

Invention relates to medicine, namely, to genetic tests for prognosing a risk of sudden death in patients with HIV and tuberculosis co-infection, including those with IRIS syndrome. Risk markers used in a method are interleukin IL-18 and genotype of locus HLA-DQB1 class II genes. Izgudrojums attieca...

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Hauptverfasser: JANUŠKEVIČA, Inga, VĪKSNA, Ludmila, KOĻESOVA, Oksana, HAGINA, Elvīra, STŪRE, Gunta, STOROŽENKO, Jeļena, KOĻESOVS, Aleksandrs, KRAMIČA, Ksenija, ROZENTĀLE, Baiba, EGLĪTE, Jeļena, JASINSKIS, Vladislavs
Format: Patent
Sprache:eng ; lav
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Zusammenfassung:Invention relates to medicine, namely, to genetic tests for prognosing a risk of sudden death in patients with HIV and tuberculosis co-infection, including those with IRIS syndrome. Risk markers used in a method are interleukin IL-18 and genotype of locus HLA-DQB1 class II genes. Izgudrojums attiecas uz medicīnu, konkrētāk, uz pēkšņas nāves riska prognozēšanu slimniekiem ar HIV un tuberkulozes koinfekciju, ietverot arī pacientus ar IRIS sindromu, izmantojot ģenētiskos testus. Par riska marķieri tiek izmantots interleikīnu IL-18 un genotipa HLA II klases lokuss HLA-DQB1.