MODIFIED HBV CORE NANO-CONTAINERS AS UNIVERSAL PLATFORM FOR EXHIBITING BIOLOGICAL MATERIAL

Invention relates to molecular biology and biomedicine. It describes a method for production of nano-containers of modified hepatitis B virus. The method provides for substitution of four selected the most outwardly extended residues of amino acids of the surface of HBc particles by residues of lysi...

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Hauptverfasser: RENHOFA REG NA, STRODS ARNIS, OSE-KLINKL VA VELTA, PRIEDE DACE, KALNI Š GINTS, PUMP NS PAULS, CIEL NS INDULIS
Format: Patent
Sprache:eng ; lav
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Zusammenfassung:Invention relates to molecular biology and biomedicine. It describes a method for production of nano-containers of modified hepatitis B virus. The method provides for substitution of four selected the most outwardly extended residues of amino acids of the surface of HBc particles by residues of lysine. Izgudrojums attiecas uz molekulāro bioloģiju un biomedicīnu. Tas apraksta modificēta B hepatīta vīrusa (HBV) core (HBc) nanokonteineru iegūšanas paņēmienu, kas paredz četru izvēlēto, maksimāli uz āru izvirzītas uz HBc daļiņas virsmas novietoto aminoskābju atlikumu apmaiņu pret lizīna atlikumu.