METHOD FOR ATTACHING SELECTED MATERIAL TO NANO-PARTICLES OF HBV CORE PROTEIN

Invention relates to molecular biology and biomedicine. It describes a method for production of nano-containers of modified hepatitis B virus. The method provides for substitution of four selected the most outwardly extended residues of amino acids of the surface of HBc particles by residues of lysi...

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Hauptverfasser: RENHOFA REG NA, OSE-KLINKL VA VELTA, DIŠLERS ANDRIS, PUMP NS PAULS, KAZ KS ANDRIS, JACKEVI A LUDMILA
Format: Patent
Sprache:eng ; lav
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Zusammenfassung:Invention relates to molecular biology and biomedicine. It describes a method for production of nano-containers of modified hepatitis B virus. The method provides for substitution of four selected the most outwardly extended residues of amino acids of the surface of HBc particles by residues of lysine. Izgudrojums attiecas uz molekulāro bioloģiju un biomedicīnu. Tas apraksta modificēta B hepatīta vīrusa (HBV) core (HBc) nanokonteineru iegūšanas paņēmienu, kas paredz četru izvēlēto, maksimāli uz āru izvirzītas uz HBc daļiņas virsmas novietoto aminoskābju atlikumu apmaiņu pret lizīna atlikumu.