LU92155I

LU92155I

Enantiomerically pure compound of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.

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Bibliographische Detailangaben
Hauptverfasser: FUNK Lee A., Pfizer Global Reserch and Dev, MENG Jerry J., Pfizer Global Reserch and Dev, CUI Jingrong J., Pfizer Global Reserch and Dev, TRAN-Dube M. B. , Pfizer Global Reserch and Dev, NAMBU Mitchell D., Pfizer Global Reserch and Dev, SHEN-Hong Pfizer Global Reserch and Dev, PAIRISH Mason A., Pfizer Global Reserch and Dev, JIA Lei, Pfizer Global Reserch and Dev, KUNG Pei-Pei, Pfizer Global Reserch and Dev
Format: Patent
Sprache:fre
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Beschreibung
Zusammenfassung:Enantiomerically pure compound of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.