BLUTGERINNUNGSFOERDERNDE PRAEPARATION AUF BASIS VON HUMANPROTEINEN SOWIE VERFAHREN ZU IHRER HERSTELLUNG

BLUTGERINNUNGSFOERDERNDE PRAEPARATION AUF BASIS VON HUMANPROTEINEN SOWIE VERFAHREN ZU IHRER HERSTELLUNG

In a method of producing a blood-coagulation-promoting preparation based on human proteins and having a content of coagulation factors II, VII, IX and X and factor-VIII-inhibitor-bypassing-activity (FEIBA), human plasma is treated with sulphated high-polymer carbohydrates and/or with basic ion excha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PHILAPITSCH A, SCHWARZ O, EIBL J, ELSINGER F
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:In a method of producing a blood-coagulation-promoting preparation based on human proteins and having a content of coagulation factors II, VII, IX and X and factor-VIII-inhibitor-bypassing-activity (FEIBA), human plasma is treated with sulphated high-polymer carbohydrates and/or with basic ion exchangers, the protein mixture with generated FEIB-activity is adsorbed on the ion exchanger, and the preparation is gained by elution and concentration.