STREPTOCOCCUS SUIS (S. SUIS) VACCINE
The present disclosure provides a Streptococcus suis (S. suis) vaccine, and relates to the field of veterinary vaccines. For the S. suis vaccine, an antigen is a protein with an amino acid sequence shown in SEQ ID NO: 2. It also provides a preparation method of the S. suis vaccine, including the fol...
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| creator | ZHOU Junming ZHU Haodan FAN Hongjie NIU Jiaqiang XIAO Qi WANG Dandan ZHAO Xialing QIAN Wenxian WEN Libin HUANG Xiaoguo NI Yanxiu HE Kongwang |
| description | The present disclosure provides a Streptococcus suis (S. suis) vaccine, and relates to the field of veterinary vaccines. For the S. suis vaccine, an antigen is a protein with an amino acid sequence shown in SEQ ID NO: 2. It also provides a preparation method of the S. suis vaccine, including the following steps: mixing a white oil and aluminum stearate to obtain a white oil adjuvant; adding Tween-80 to an aqueous solution of the protein with the amino acid sequence, and thoroughly mixing to obtain an antigen solution; and mixing the antigen solution with the white oil adjuvant according to a volume ratio of (0.5-1.5):2, and emulsifying to obtain the S. suis vaccine. An animal immunized with the S. suis vaccine of the present disclosure can effectively resist the attack of S. suis serotype 2, 3, and 31, with a vaccine protection rate as high as 100%. |
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SUIS) VACCINE</title><source>esp@cenet</source><creator>ZHOU Junming ; ZHU Haodan ; FAN Hongjie ; NIU Jiaqiang ; XIAO Qi ; WANG Dandan ; ZHAO Xialing ; QIAN Wenxian ; WEN Libin ; HUANG Xiaoguo ; NI Yanxiu ; HE Kongwang</creator><creatorcontrib>ZHOU Junming ; ZHU Haodan ; FAN Hongjie ; NIU Jiaqiang ; XIAO Qi ; WANG Dandan ; ZHAO Xialing ; QIAN Wenxian ; WEN Libin ; HUANG Xiaoguo ; NI Yanxiu ; HE Kongwang</creatorcontrib><description>The present disclosure provides a Streptococcus suis (S. suis) vaccine, and relates to the field of veterinary vaccines. For the S. suis vaccine, an antigen is a protein with an amino acid sequence shown in SEQ ID NO: 2. It also provides a preparation method of the S. suis vaccine, including the following steps: mixing a white oil and aluminum stearate to obtain a white oil adjuvant; adding Tween-80 to an aqueous solution of the protein with the amino acid sequence, and thoroughly mixing to obtain an antigen solution; and mixing the antigen solution with the white oil adjuvant according to a volume ratio of (0.5-1.5):2, and emulsifying to obtain the S. suis vaccine. An animal immunized with the S. suis vaccine of the present disclosure can effectively resist the attack of S. suis serotype 2, 3, and 31, with a vaccine protection rate as high as 100%.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230228&DB=EPODOC&CC=LU&NR=503542A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230228&DB=EPODOC&CC=LU&NR=503542A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHOU Junming</creatorcontrib><creatorcontrib>ZHU Haodan</creatorcontrib><creatorcontrib>FAN Hongjie</creatorcontrib><creatorcontrib>NIU Jiaqiang</creatorcontrib><creatorcontrib>XIAO Qi</creatorcontrib><creatorcontrib>WANG Dandan</creatorcontrib><creatorcontrib>ZHAO Xialing</creatorcontrib><creatorcontrib>QIAN Wenxian</creatorcontrib><creatorcontrib>WEN Libin</creatorcontrib><creatorcontrib>HUANG Xiaoguo</creatorcontrib><creatorcontrib>NI Yanxiu</creatorcontrib><creatorcontrib>HE Kongwang</creatorcontrib><title>STREPTOCOCCUS SUIS (S. 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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | STREPTOCOCCUS SUIS (S. SUIS) VACCINE |
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