STREPTOCOCCUS SUIS (S. SUIS) VACCINE

The present disclosure provides a Streptococcus suis (S. suis) vaccine, and relates to the field of veterinary vaccines. For the S. suis vaccine, an antigen is a protein with an amino acid sequence shown in SEQ ID NO: 2. It also provides a preparation method of the S. suis vaccine, including the following steps: mixing a white oil and aluminum stearate to obtain a white oil adjuvant; adding Tween-80 to an aqueous solution of the protein with the amino acid sequence, and thoroughly mixing to obtain an antigen solution; and mixing the antigen solution with the white oil adjuvant according to a volume ratio of (0.5-1.5):2, and emulsifying to obtain the S. suis vaccine. An animal immunized with the S. suis vaccine of the present disclosure can effectively resist the attack of S. suis serotype 2, 3, and 31, with a vaccine protection rate as high as 100%.