Asiaticoside-chitosan-sodium Alginate Microsphere and Preparation Method and Application thereof

Asiaticoside-chitosan-sodium Alginate Microsphere and Preparation Method and Application thereof

The invention discloses asiaticoside-chitosan-sodium alginate microspheres, preparation method and application thereof, belonging to the technical field of biomedical materials. The microsphere is prepared by adopting an emulsification cross-linking method and finally freeze-drying, and the preparat...

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Hauptverfasser: LI Sidong, CAI Tingting, GUO Jiaqi, KONG Songzhi, QUAN Weiyan, YE Weixia
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator LI Sidong
CAI Tingting
GUO Jiaqi
KONG Songzhi
QUAN Weiyan
YE Weixia
description The invention discloses asiaticoside-chitosan-sodium alginate microspheres, preparation method and application thereof, belonging to the technical field of biomedical materials. The microsphere is prepared by adopting an emulsification cross-linking method and finally freeze-drying, and the preparation method comprises the following steps: 1) preparing sodium alginate solution and asiaticoside-chitosan acetic acid solution respectively; 2) slowly and uniformly dripping sodium alginate solution into the oil phase, and stirring at high speed to form colostrum; 3) the asiaticoside-chitosan acetic acid solution is slowly and evenly dripped into colostrum, stirred and fully emulsified; and 4) slowly and uniformly dripping glyceraldehyde solution for crosslinking and curing, centrifuging, washing the precipitate with petroleum ether and absolute ethanol in turn, and vacuum freeze-drying to obtain the pale yellow powder of asiaticoside-sodium alginate-chitosan microspheres.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Asiaticoside-chitosan-sodium Alginate Microsphere and Preparation Method and Application thereof
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