Asiaticoside-chitosan-sodium Alginate Microsphere and Preparation Method and Application thereof

The invention discloses asiaticoside-chitosan-sodium alginate microspheres, preparation method and application thereof, belonging to the technical field of biomedical materials. The microsphere is prepared by adopting an emulsification cross-linking method and finally freeze-drying, and the preparation method comprises the following steps: 1) preparing sodium alginate solution and asiaticoside-chitosan acetic acid solution respectively; 2) slowly and uniformly dripping sodium alginate solution into the oil phase, and stirring at high speed to form colostrum; 3) the asiaticoside-chitosan acetic acid solution is slowly and evenly dripped into colostrum, stirred and fully emulsified; and 4) slowly and uniformly dripping glyceraldehyde solution for crosslinking and curing, centrifuging, washing the precipitate with petroleum ether and absolute ethanol in turn, and vacuum freeze-drying to obtain the pale yellow powder of asiaticoside-sodium alginate-chitosan microspheres.