ANTIDIURETIC PREPARATION AND PROCESS FOR PREPARATION THEREOF

This invention belongs to the field of medicine. The aim of the invention is to increase an antidiuretic preparation pharmaceutical therapy activity and improve the production method thereof. An antidiuretic preparation contains active substances, secreted by the posterior pituitary gland, and a pre...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GERBUTAVICIENE,RIMA-JURATE, KLIMAS,RIMANTAS, GENDROLIS,ANTANAS-JUOZAS, MACIULEVICIUS,JONAS, BUDNIKAS,VYTAUTAS
Format: Patent
Sprache:eng ; lit
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:This invention belongs to the field of medicine. The aim of the invention is to increase an antidiuretic preparation pharmaceutical therapy activity and improve the production method thereof. An antidiuretic preparation contains active substances, secreted by the posterior pituitary gland, and a preservative. It consists of the following components:chromatographically purified vasopressin - 0.01 g,chlorobutanolhydrate - 5.0 g,sodium acetate - 2.2 g,ice acetic acid (0.1 mol/l concentration) - 836.6 ml,sodium chloride - 6.8 g,injection water up to 1,000 ml solution.The active substance, chromatographically purified vasopressin, is dissolved in an acetate buffer solution, isotonic by sodium chloride, the solution is preserved by chlorobutanolhydrate, it is filtered and poured into ampoules. The advantage of such a preparation is increased biological and pharmaceutical therapy activity, no present outside albumen admixtures.