PROCESS FOR PREPARING PURE ISOFLAVONE DERIVATIVES

PROCESS FOR PREPARING PURE ISOFLAVONE DERIVATIVES

PCT No. PCT/HU90/00023 Sec. 371 Date Dec. 5, 1991 Sec. 102(e) Date Dec. 5, 1991 PCT Filed Apr. 6, 1990 PCT Pub. No. WO91/15483 PCT Pub. Date Oct. 17, 1991.The invention relates to a process for the preparation of pure isoflavone derivatives of the general formula (I), (I) wherein R stands for hydrog...

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Hauptverfasser: SOMFAI,EVA, LANYI,GYORGY, KALLAY,TAMAS, LEDNICZKY,LASZLO, IMREI,LAJOS, HOFFMANN,GYORGY, MONTAY,TIBOR, SZILADI,MARIA
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PCT No. PCT/HU90/00023 Sec. 371 Date Dec. 5, 1991 Sec. 102(e) Date Dec. 5, 1991 PCT Filed Apr. 6, 1990 PCT Pub. No. WO91/15483 PCT Pub. Date Oct. 17, 1991.The invention relates to a process for the preparation of pure isoflavone derivatives of the general formula (I), (I) wherein R stands for hydrogen or isopropyl, R2 and R3 stand for hydrogen or C1-2 alkoxy by reacting a rezorcinol-derivative of the general formula (III) (III) wherein R2 and R3 are as given above with ethyl-orthoformiate of the formula (IV) (C2H5O)3l CH(IV) in the presence of a base and optionally by alkylating the product.