PROTEASE-ACTIVATED T CELL BISPECIFIC MOLECULES

The present invention generally relates to novel protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides. The present invention also relates to polynucleotides encoding such protease-activatable T cell activating bispecific molecules and idiotype-specific polyp...

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Bibliographische Detailangaben
Hauptverfasser:	SULLIVAN, Eric, SCHANZER, Juergen Michael, CROASDALE-WOOD, Rebecca, GEIGER, Martina, PATEL, Jigar, UMANA, Pablo, KLEIN, Christian, BRUENKER, Peter, STUBENRAUCH, Kay-Gunnar
Format:	Patent
Sprache:	eng ; lit
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention generally relates to novel protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides. The present invention also relates to polynucleotides encoding such protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides of the invention, and to methods of using these protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides in the treatment of disease.