INHIBITORS OF INFLUENZA VIRUSES REPLICATION

Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a c...

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Bibliographische Detailangaben
Hauptverfasser:	WANG, Tiansheng, LEDFORD, Brian, LIN, Chao, JACOBS, Dylan, DUFFY, John, SALITURO, Francesco G, CLARK, Michael, KENNEDY, Joseph, GAO, Huai, LEDEBOER, Mark, MALTAIS, Francois, COURT, John, JONES, Steven, BANDARAGE, Upul, KWONG, Ann Dak-Yee, GU, Wenxin, PEROLA, Emanuele, GERMANN, Ursula, FARMER, Luc, BYRN, Randal, BETHIEL, Randy, WANNAMAKER, M, DENG, Hongbo, ZHOU, Yi, CHARIFSON, Paul, JIANG, Min, DRUTU, Ioana
Format:	Patent
Sprache:	eng ; lit
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula ( I ): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula ( IA ) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula ( IA ) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.