HETEROBICYCLOARYL RORC2 INHIBITORS AND METHODS OF USE THEREOF

The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.

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Bibliographische Detailangaben
Hauptverfasser:	ZAPF, Christoph Wolfgang, XING, Li, WENNERSTÅL, Göran Mattias, SCHNUTE, Mark Edward, KAILA, Neelu, MEYERS, Marvin Jay, BLINN, James Robert, MENTE, Scot Richard, THORARENSEN, Atli, ZAMARATSKI, Edouard, FLICK, Andrew Christopher, JONES, Peter, KIEFER, James Richard Jr, KURUMBAIL, Ravi G
Format:	Patent
Sprache:	eng ; lit
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.