ENTERIC COATED TABLET

To provide an enteric coated tablet containing a large amount of medicinal ingredient and having sufficient impact resistance, without forming a thick enteric coating layer. The enteric coated tablet contains (A) a core tablet containing a medicinal ingredient and having a weight of 1,000 mg or more...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RYU, Akio, OSADA, Miyako
Format: Patent
Sprache:eng ; lit
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Beschreibung
Zusammenfassung:To provide an enteric coated tablet containing a large amount of medicinal ingredient and having sufficient impact resistance, without forming a thick enteric coating layer. The enteric coated tablet contains (A) a core tablet containing a medicinal ingredient and having a weight of 1,000 mg or more; (B) a coating layer containing a water-soluble polymer applied onto the surface of the core tablet; and (C) an enteric coating layer dissolving at pH 7 or higher which is applied onto the surface of the coating layer containing a water-soluble polymer, wherein the sum of the polymer amount of the coating layer (B) and the polymer amount of the coating layer (C) is 10 to 18 mg/cm 2 , the polymer amount of the coating layer (B) is 6 to 12 mg/cm 2 , and the polymer amount of the coating layer (C) is 3 to 6 mg/cm 2 .