THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS

The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and...

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Bibliographische Detailangaben
Hauptverfasser:	PÉREZ DE LA CRUZ MORENO, Maria Angeles, MEDINA PADILLA, Miguel, DE CRISTOBAL BLANCO, Javier, PALOMO NICOLAU, Francisco, DOMINGUEZ CORREA, Juan Manuel, HERRERO SANTOS, Susana, MARTINEZ MONTERO, Olga, FUERTES HUERTA, Ana, SANCHEZ-QUESADA, Jorge, LOPEZ OGALLA, Javier, RODRIGUEZ SALGUERO, Beatriz
Format:	Patent
Sprache:	eng ; lit
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them.