INDOLE AND INDAZOLE COMPOUNDS THAT ACTIVATE AMPK

The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, o...

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Bibliographische Detailangaben
Hauptverfasser:	FILIPSKI, Kevin James, CAMERON, Kimberly O`Keefe, FERNANDO, Dilinie Prasadhini, LEE, Esther Cheng Yin, EBNER, David Christopher, TU, Meihua Mike, DOWLING, Matthew Scott, BHATTACHARYA, Samit Kumar, SMITH, Aaron Christopher, KUNG, Daniel Wei-Shung
Format:	Patent
Sprache:	eng ; lit
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.