STABLE PHARMACEUTICAL COMPOSITION COMPRISING AMORPHOUS ROSUVASTATIN CALCIUM

This invention concerns a novel tablet pharmaceutical composition, used for the treatment hyperlipoproteinemia, hypercholesterolaemia and atherosclerosis. The composition related to this invention comprises amorphous rosuvastatin calcium, stabilized by adding calcium carbonate in a ratio of 0,5...2:...

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Bibliographische Detailangaben
Hauptverfasser:	TELISCA, Amalia-Diana, MOISUC, Lacramioara Stefania, MACOVEI, Lenuta, Saraficeanu, Nicoleta, POTUR, Roxana-Georgiana, BOITA, Tudor
Format:	Patent
Sprache:	eng ; lit
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	This invention concerns a novel tablet pharmaceutical composition, used for the treatment hyperlipoproteinemia, hypercholesterolaemia and atherosclerosis. The composition related to this invention comprises amorphous rosuvastatin calcium, stabilized by adding calcium carbonate in a ratio of 0,5...2:1 (w/w) and other excipients: 30...60% lactose monohydrate, 15...35% microcrystalline cellulose, 1...5% crospovidone and 0,25...5% magnesium stearate.